The average bus between Como and Genova Brignole takes 7h 38m and the fastest bus takes 3h 22m. The bus service runs several times per day from Como to Genova Brignole. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Como and Genova Brignole. The earliest departure is at 6:25 AM in the morning, and the last departure from Como is at 8:20 PM which arrives into Genova Brignole at 10:59 AM. All services require a transfer at Milano, Autostazione Lampugnano and take an average of 7h 38m. The schedules shown below are for the next available departures.


5h 22m • 2 changes


10h 28m • 2 changes
Arrives next day


14h 22m • 2 changes


5h 22m • 2 changes


10h 28m • 2 changes
Arrives next day


14h 39m • 2 changes
Want to know about travelling from Como to Genova Brignole? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Como to Genova Brignole. However, there are services departing from Como station and arriving at Genova Brignole station via Milan. The journey, including transfers, takes approximately 7h 38m.
Como to Genova Brignole bus services, operated by FlixBus, depart from Como station.
Como to Genova Brignole bus services, operated by FlixBus, arrive at Genoa station.
Book your Como to Genova Brignole bus tickets online with FlixBus and AMT Genova.
The distance between Como and Genova Brignole is 156.2 km. The road distance is 193 km.
You can take a bus from Como to Brignole Fs/ via Milano, Autostazione Lampugnano, Genoa, and Marittima/Principe Fs in around 4h 23m.