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Czechia to Brussels buses

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Trip Overview

The bus between Czechia and Brussels takes 12h 13m. The bus runs, on average, 2 times per week from Czechia to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 13m
Duration
938 km
Distance
€71
Average price
Twice a week
Frequency

Czechia to Brussels bus times

Buses run twice a week between Czechia and Brussels. The service departs Czechia at 5:47 PM in the evening, which arrives into Brussels at 06:00:00. All services require a transfer at Florenc and take an average of 12h 13m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Pražská integrovaná dopravaRegioJet12h 13m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Pražská integrovaná dopravaRegioJet12h 13m • 1 change

Frequently asked questions

Want to know about travelling from Czechia to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Czechia to Brussels.ExpandLaunch map view
  • Distance: 938.2 km
  • Duration: 12h 13m

What companies run services between Czechia and Brussels, Belgium?

RegioJet operates a bus from Prague Florenc Central Bus Station to Brussels Midi / Brussels South West 4 times a week. Tickets cost €55–100 and the journey takes 12h.

Operators