The average bus between Düsseldorf Central Station and Milan takes 14h 16m and the fastest bus takes 13h 14m. The bus service runs several times per day from Düsseldorf Central Station to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Düsseldorf Central Station and Milan. The earliest departure is at 1:45 AM at night, and the last departure from Düsseldorf Central Station is at 7:40 PM which arrives into Milan at 1:37 PM. All services require a transfer at Düsseldorf central bus station and take an average of 14h 16m. The schedules shown below are for the next available departures.

15h 14m • 1 change
Arrives next day

15h 54m • 1 change
Arrives next day

17h 47m • 1 change

15h 14m • 1 change
Arrives next day

15h 54m • 1 change
Arrives next day

17h 47m • 1 change

15h 14m • 1 change
Arrives next day

15h 54m • 1 change
Arrives next day

17h 47m • 1 change

15h 14m • 1 change
Arrives next day

15h 55m • 1 change
Arrives next day

17h 57m • 1 change
Want to know about travelling from Düsseldorf Central Station to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Düsseldorf Central Station to Milan. However, there are services departing from Düsseldorf Central Station station and arriving at Milan station via Milan. The journey, including transfers, takes approximately 14h 16m.
Düsseldorf Central Station to Milan bus services, operated by FlixBus, depart from Düsseldorf central bus station.
Düsseldorf Central Station to Milan bus services, operated by FlixBus, arrive at Milan station.
The distance between Düsseldorf Central Station and Milan is 664 km. The road distance is 894 km.
FlixBus operates a bus from Düsseldorf central bus station to Milan 3 times a day. Tickets cost €70–120 and the journey takes 13h 5m.