The average bus between DePaul University and Indianapolis takes 5h 1m and the fastest bus takes 4h 9m. The bus service runs several times per day from DePaul University to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between DePaul University and Indianapolis. The earliest departure is at 6:05 AM in the morning, and the last departure from DePaul University is at 6:55 PM which arrives into Indianapolis at 11:50 AM. All services require a transfer at Fullerton and take an average of 5h 1m. The schedules shown below are for the next available departures.

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Want to know about travelling from DePaul University to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from DePaul University to Indianapolis. However, there are services departing from DePaul University station and arriving at Indianapolis station via Indianapolis Union Station station. The journey, including transfers, takes approximately 5h 1m.
DePaul University to Indianapolis bus services, operated by Chicago Transit (CTA), depart from Chicago station.
DePaul University to Indianapolis bus services, operated by Chicago Transit (CTA), arrive at Indianapolis Union Station.
The distance between DePaul University and Indianapolis is 270.6 km. The road distance is 301 km.
Greyhound USA operates a bus from Chicago to Indianapolis Union Station once daily. Tickets cost $27–55 and the journey takes 3h 30m.