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DePaul University to Indianapolis buses

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Trip Overview

The average bus between DePaul University and Indianapolis takes 5h 39m and the fastest bus takes 3h 48m. The bus service runs several times per day from DePaul University to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 39m
Duration
185 mi
Distance
$42
Average price
3 times a day
Frequency

DePaul University to Indianapolis bus times

Buses run 3 times a day between DePaul University and Indianapolis. The earliest departure is at 9:10 AM in the morning, and the last departure from DePaul University is at 6:55 PM which arrives into Indianapolis at 4:15 AM. All services require a transfer at Fullerton & Sheffield and take an average of 5h 39m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Chicago Transit (CTA)Greyhound USA4h 54m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA5h 36m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA3h 48m • 1 change
  •  → 

    Arrives next day

    Chicago Transit (CTA)Greyhound USA8h 19m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Chicago Transit (CTA)Greyhound USA4h 54m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA5h 36m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA3h 48m • 1 change
  •  → 

    Arrives next day

    Chicago Transit (CTA)Greyhound USA8h 19m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Chicago Transit (CTA)Greyhound USA4h 54m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA5h 36m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA3h 48m • 1 change
  •  → 

    Arrives next day

    Chicago Transit (CTA)Greyhound USA8h 19m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Chicago Transit (CTA)Greyhound USA4h 54m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA5h 36m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA3h 48m • 1 change
  •  → 

    Arrives next day

    Chicago Transit (CTA)Greyhound USA8h 19m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Chicago Transit (CTA)Greyhound USA4h 54m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA5h 36m • 1 change
  •  → 

    Chicago Transit (CTA)Greyhound USA3h 48m • 1 change
  •  → 

    Arrives next day

    Chicago Transit (CTA)Greyhound USA8h 19m • 1 change

Frequently asked questions

Want to know about travelling from DePaul University to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from DePaul University to Indianapolis.ExpandLaunch map view
  • Distance: 184.7 mi
  • Duration: 5h 39m

What companies run services between DePaul University, IL, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station every 3 hours. Tickets cost $30–50 and the journey takes 3h 5m.

Operators