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Denver, CO to Indianapolis buses

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Trip Overview

The average bus between Denver, CO and Indianapolis takes 28h 50m and the fastest bus takes 26h 15m. The bus runs, on average, 6 times per week from Denver, CO to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 50m
Duration
1,201 mi
Distance
$251
Average price
6 times a week
Frequency

Denver, CO to Indianapolis bus times

Buses run 6 times a week between Denver, CO and Indianapolis. The service departs Denver, CO at 6:55 PM in the evening, which arrives into Indianapolis at 23:10:00. All services require a transfer at Denver Union Station and take an average of 28h 50m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA27h 15m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA26h 15m • 1 change

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USA39h 50m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USA27h 10m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USA26h 15m • 1 change

Frequently asked questions

Want to know about travelling from Denver, CO to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Denver, CO to Indianapolis.ExpandLaunch map view
  • Distance: 1,201.2 mi
  • Duration: 28h 50m

What companies run services between Denver, CO, USA and Indianapolis, IN, USA?

You can take a vehicle from Denver, CO to Indianapolis via Denver Union Station and Chicago Bus Station in around 25h 33m.

Operators