The average bus between Derby and Aylesbury takes 4h 37m and the fastest bus takes 4h 8m. The bus service runs several times per day from Derby to Aylesbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Derby and Aylesbury. The earliest departure is at 2:25 AM at night, and the last departure from Derby is at 12:15 PM which arrives into Aylesbury at 4:48 PM. All services require a transfer at Milton Keynes Coachway and take an average of 4h 37m. The schedules shown below are for the next available departures.


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5h 18m • 2 changes


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4h 8m • 2 changes
Want to know about travelling from Derby to Aylesbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Derby to Aylesbury. However, there are services departing from Derby station and arriving at Aylesbury station via Milton Keynes Coachway. The journey, including transfers, takes approximately 4h 37m.
Derby to Aylesbury bus services, operated by National Express, depart from Bus Station.
Derby to Aylesbury bus services, operated by National Express, arrive at Cambridge Street station.
The distance between Derby and Aylesbury is 130.9 km. The road distance is 190 km.
You can take a bus from Bus Station to Cambridge Street via Milton Keynes Coachway and The Point in around 4h 29m.