The average bus between Des Moines and Harrisonburg takes 37h and the fastest bus takes 30h 25m. There is at least one bus per day from Des Moines to Harrisonburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and Harrisonburg. The earliest departure is at 9:20 AM in the morning, and the last departure from Des Moines is at 9:45 AM which arrives into Harrisonburg at 12:55 PM. All services require a transfer at Chicago Bus Station and take an average of 37h. The schedules shown below are for the next available departures.
Arrives next day


31h 25m • 2 changes
Arrives +2 days


2d 3h • 2 changes
Arrives next day


31h 25m • 2 changes
Arrives +2 days


2d 3h • 2 changes
Want to know about travelling from Des Moines to Harrisonburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Harrisonburg. However, there are services departing from Des Moines station and arriving at Harrisonburg station via Chicago Bus Station station. The journey, including transfers, takes approximately 37h.
Des Moines to Harrisonburg bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Harrisonburg bus services, operated by Greyhound USA, arrive at Godwin Transit Center station.
Book your Des Moines to Harrisonburg bus tickets online with Greyhound USA and Virginia Breeze.
The distance between Des Moines and Harrisonburg is 1,301.2 km. The road distance is 1,935 km.
You can take a bus from Des Moines to Godwin Transit Center via Chicago Bus Station and Washington Union Station in around 29h.