The average bus between Des Moines and Jacksonville takes 37h 57m and the fastest bus takes 36h 50m. There is at least one bus per day from Des Moines to Jacksonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and Jacksonville. The earliest departure is at 9:15 AM in the morning, and the last departure from Des Moines is at 9:15 AM which arrives into Jacksonville at 11:05 PM. All services require a transfer at St Louis Bus Station and take an average of 37h 57m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Jacksonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Jacksonville. However, there are services departing from Des Moines station and arriving at Jacksonville station via St Louis Bus Station station. The journey, including transfers, takes approximately 37h 57m.
Des Moines to Jacksonville bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Jacksonville bus services, operated by Greyhound USA, arrive at Jacksonville station.
Book your Des Moines to Jacksonville bus tickets online with Greyhound USA and Flixbus USA.
The distance between Des Moines and Jacksonville is 1,648.1 km. The road distance is 2,191 km.
You can take a bus from Des Moines to Jacksonville via St Louis Bus Station and Atlanta Bus Station in around 28h 35m.
