The bus between Des Moines and Jacksonville takes 34h 50m. The bus runs, on average, 6 times per week from Des Moines to Jacksonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Des Moines and Jacksonville. The earliest departure is at 8:05 AM in the morning, and the last departure from Des Moines is at 8:05 AM which arrives into Jacksonville at 7:55 PM. All services require a transfer at Indianapolis Union Station and take an average of 34h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Jacksonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Jacksonville. However, there are services departing from Des Moines station and arriving at Jacksonville station via Indianapolis Union Station station. The journey, including transfers, takes approximately 34h 50m.
Des Moines to Jacksonville bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Jacksonville bus services, operated by Greyhound USA, arrive at Jacksonville station.
Book your Des Moines to Jacksonville bus tickets online with Greyhound USA.
The distance between Des Moines and Jacksonville is 1,648.1 km. The road distance is 2,225 km.
You can take a bus from Des Moines to Jacksonville via Indianapolis Union Station and Atlanta Bus Station in around 29h 40m.
