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Des Moines to Louisiana buses

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Trip Overview

The average bus between Des Moines and Louisiana takes 39h 25m and the fastest bus takes 38h 30m. The bus runs, on average, 5 times per week from Des Moines to Louisiana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 25m
Duration
1,146 mi
Distance
$263
Average price
5 times a week
Frequency

Des Moines to Louisiana bus times

Buses run 5 times a week between Des Moines and Louisiana. The earliest departure is at 4:20 AM at night, and the last departure from Des Moines is at 11:45 PM which arrives into Louisiana at 5:50 PM. All services require a transfer at Kansas City and take an average of 39h 25m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USAGreyhound USA43h 5m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA38h 30m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA38h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Des Moines to Louisiana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Louisiana.ExpandLaunch map view
  • Distance: 1,146 mi
  • Duration: 39h 25m

What companies run services between Des Moines, IA, USA and Louisiana, USA?

You can take a bus from Des Moines to New Orleans Bus Station via Kansas City, Kansas City Bus Station, and St Louis Bus Station in around 26h 20m.

Operators