The bus between Des Moines and Louisville takes 12h 25m. There is at least one bus per day from Des Moines to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and Louisville. The earliest departure is at 4:55 AM at night, and the last departure from Des Moines is at 4:55 AM which arrives into Louisville at 6:20 PM. All services require a transfer, and take on average 12h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Louisville. However, there are services departing from Des Moines station and arriving at Louisville station via Indianapolis Union Station station. The journey, including transfers, takes approximately 12h 25m.
Des Moines to Louisville bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Louisville bus services, operated by Greyhound USA, arrive at Louisville, KY station.
Book your Des Moines to Louisville bus tickets online with Greyhound USA and Amtrak Thruway.
The distance between Des Moines and Louisville is 765.4 km. The road distance is 928 km.
You can take a bus from Des Moines to Louisville, KY via Indianapolis Union Station in around 13h 5m.
