The average bus between Des Moines and McAllen takes 39h 7m and the fastest bus takes 33h 45m. There is at least one bus per day from Des Moines to McAllen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Des Moines and McAllen. The earliest departure is at 4:20 AM at night, and the last departure from Des Moines is at 11:45 PM which arrives into McAllen at 8:00 PM. All services require a transfer at Kansas City and take an average of 39h 7m. The schedules shown below are for the next available departures.
Arrives +2 days


33h 45m • 2 changesArrives +2 days


45h 15m • 2 changesArrives +2 days


33h 45m • 2 changesArrives +2 days


45h 15m • 2 changesWant to know about travelling from Des Moines to McAllen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to McAllen. However, there are services departing from Des Moines station and arriving at McAllen station via Kansas City. The journey, including transfers, takes approximately 39h 7m.
Des Moines to McAllen bus services, operated by Jefferson Lines, depart from Des Moines station.
Des Moines to McAllen bus services, operated by Jefferson Lines, arrive at McAllen Central Station.
Book your Des Moines to McAllen bus tickets online with Jefferson Lines, Greyhound USA and Flixbus USA.
The distance between Des Moines and McAllen is 1,763.7 km. The road distance is 2,171 km.
You can take a bus from Des Moines to McAllen Central Station via Kansas City, Kansas City Bus Station, and Dallas Bus Station in around 30h 35m.