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Des Moines to North Carolina buses

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Trip Overview

The bus between Des Moines and North Carolina takes 43h 55m. The bus runs, on average, 6 times per week from Des Moines to North Carolina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 55m
Duration
1,110 mi
Distance
$226
Average price
6 times a week
Frequency

Des Moines to North Carolina bus times

Buses run 6 times a week between Des Moines and North Carolina. The service departs Des Moines at 7:50 AM in the morning, which arrives into North Carolina at 04:45:00. All services require a transfer at Indianapolis Union Station and take an average of 43h 55m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Departing Wednesday, November 4, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Departing Thursday, November 5, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Departing Friday, November 6, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Departing Saturday, November 7, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USABarons Bus43h 55m • 2 changes

Frequently asked questions

Want to know about travelling from Des Moines to North Carolina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to North Carolina.ExpandLaunch map view
  • Distance: 1,109.7 mi
  • Duration: 43h 55m

What companies run services between Des Moines, IA, USA and North Carolina, USA?

You can take a bus from Des Moines to Charlotte via Indianapolis Union Station and Columbus in around 26h 30m.

Operators