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Des Moines to Pennsylvania buses

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Trip Overview

The bus between Des Moines and Pennsylvania takes 28h 20m. The bus runs, on average, 6 times per week from Des Moines to Pennsylvania. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 20m
Duration
1,130 mi
Distance
$238
Average price
6 times a week
Frequency

Des Moines to Pennsylvania bus times

Buses run 6 times a week between Des Moines and Pennsylvania. The service departs Des Moines at 7:50 AM in the morning, which arrives into Pennsylvania at 13:10:00. All services require a transfer, and take on average 28h 20m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USA28h 20m • 1 change

Frequently asked questions

Want to know about travelling from Des Moines to Pennsylvania? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Pennsylvania.ExpandLaunch map view
  • Distance: 1,130 mi
  • Duration: 28h 20m

What companies run services between Des Moines, IA, USA and Pennsylvania, USA?

You can take a bus from Des Moines to Philadelphia Bus Station via Indianapolis Union Station in around 27h.

Operators