Download the Rome2Rio travel app
Scan QR code with your phone to download the app
Scan QR code with your phone to download the app
The average bus between Des Moines and Port Saint Lucie takes 2d 6h and the fastest bus takes 2d 2h. The bus runs, on average, 5 times per week from Des Moines to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Des Moines and Port Saint Lucie. The service departs Des Moines at 7:50 AM in the morning, which arrives into Port Saint Lucie at 11:52:00. All services require a transfer at Indianapolis Union Station and take an average of 2d 6h. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Port Saint Lucie. However, there are services departing from Des Moines station and arriving at Port St Lucie station via Indianapolis Union Station and Atlanta Bus Station. The journey, including transfers, takes approximately 2 days 6h.
Des Moines to Port Saint Lucie bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Port Saint Lucie bus services, operated by Flixbus USA, arrive at Port St Lucie station.
The distance between Des Moines and Port Saint Lucie is 1997 km. The road distance is 2287 km.
You can take a bus from Des Moines to SW PSL Blvd & SE Bayshore Blvd via Indianapolis Union Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 35h 9m.
