The bus between Des Moines and Port Saint Lucie takes 42h 32m. The bus runs, on average, 5 times per week from Des Moines to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Des Moines and Port Saint Lucie. The earliest departure is at 4:20 PM in the afternoon, and the last departure from Des Moines is at 4:20 PM which arrives into Port Saint Lucie at 11:52 AM. All services require a transfer at St Louis Bus Station and take an average of 42h 32m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Port Saint Lucie. However, there are services departing from Des Moines station and arriving at Port Saint Lucie station via St Louis Bus Station station. The journey, including transfers, takes approximately 42h 32m.
Des Moines to Port Saint Lucie bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Port Saint Lucie bus services, operated by Greyhound USA, arrive at Port St Lucie station.
The distance between Des Moines and Port Saint Lucie is 1,997 km. The road distance is 2,473 km.
You can take a bus from Des Moines to SW PSL Blvd & SE Bayshore Blvd via St Louis Bus Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 33h 9m.
