The bus between Des Moines and Roanoke takes 42h 35m. The bus runs, on average, 6 times per week from Des Moines to Roanoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Des Moines and Roanoke. The earliest departure is at 8:05 AM in the morning, and the last departure from Des Moines is at 8:05 AM which arrives into Roanoke at 3:40 AM. All services require a transfer at Indianapolis Union Station and take an average of 42h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Roanoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Roanoke. However, there are services departing from Des Moines station and arriving at Roanoke station via Indianapolis Union Station station. The journey, including transfers, takes approximately 42h 35m.
Des Moines to Roanoke bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Roanoke bus services, operated by Greyhound USA, arrive at Roanoke Bus Stop station.
Book your Des Moines to Roanoke bus tickets online with Greyhound USA.
The distance between Des Moines and Roanoke is 1,266.8 km. The road distance is 1,908 km.
You can take a bus from Des Moines to Roanoke Bus Stop via Indianapolis Union Station and Nashville Bus Station in around 25h 25m.
