The average bus between Des Moines and San Antonio takes 46h 22m and the fastest bus takes 44h 5m. The bus runs, on average, 4 times per week from Des Moines to San Antonio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between Des Moines and San Antonio. The earliest departure is at 4:20 AM at night, and the last departure from Des Moines is at 11:45 PM which arrives into San Antonio at 11:25 PM. All services require a transfer at Kansas City and take an average of 46h 22m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to San Antonio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to San Antonio. However, there are services departing from Des Moines station and arriving at San Antonio station via Kansas City. The journey, including transfers, takes approximately 46h 22m.
Des Moines to San Antonio bus services, operated by Jefferson Lines, depart from Des Moines station.
Des Moines to San Antonio bus services, operated by Jefferson Lines, arrive at San Antonio Bus Station.
Book your Des Moines to San Antonio bus tickets online with Jefferson Lines and Flixbus USA.
The distance between Des Moines and San Antonio is 1,423.6 km. The road distance is 1,691 km.
You can take a bus from Des Moines to San Antonio Bus Station via Kansas City, Kansas City Bus Station, and Denton in around 22h 35m.
