The bus between Des Moines and San Francisco takes 45h 15m. The bus runs, on average, 5 times per week from Des Moines to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Des Moines and San Francisco. The earliest departure is at 6:20 PM in the evening, and the last departure from Des Moines is at 6:20 PM which arrives into San Francisco at 12:35 PM. All services require a transfer at Denver and take an average of 45h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to San Francisco. However, there are services departing from Des Moines station and arriving at San Francisco station via Denver. The journey, including transfers, takes approximately 45h 15m.
Des Moines to San Francisco bus services, operated by Burlington Trailways, depart from Des Moines station.
Des Moines to San Francisco bus services, operated by Burlington Trailways, arrive at San Francisco Bus Station.
Book your Des Moines to San Francisco bus tickets online with Burlington Trailways and Greyhound USA.
The distance between Des Moines and San Francisco is 2,489.7 km. The road distance is 3,161 km.
You can take a bus from Des Moines to San Francisco Bus Station via Denver, Denver Union Station, and Sparks Transit Center in around 42h 9m.