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Des Moines to Tampa buses

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Trip Overview

The bus between Des Moines and Tampa takes 47h 5m. The bus runs, on average, 3 times per week from Des Moines to Tampa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 5m
Duration
1,520 mi
Distance
$301
Average price
3 times a week
Frequency

Des Moines to Tampa bus times

Buses run 3 times a week between Des Moines and Tampa. The service departs Des Moines at 7:50 AM in the morning, which arrives into Tampa at 07:55:00. All services require a transfer at Indianapolis Union Station and take an average of 47h 5m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 5m • 2 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 5m • 2 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Des Moines to Tampa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Tampa.ExpandLaunch map view
  • Distance: 1,519.5 mi
  • Duration: 47h 5m

What companies run services between Des Moines, IA, USA and Tampa, FL, USA?

You can take a bus from Des Moines to Tampa Bus Station via Indianapolis Union Station and Atlanta Bus Station in around 32h.

Operators