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Des Moines to Tampa buses

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Trip Overview

The bus between Des Moines and Tampa takes 47h 25m. The bus runs, on average, 3 times per week from Des Moines to Tampa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 25m
Duration
1,523 mi
Distance
$320
Average price
3 times a week
Frequency

Des Moines to Tampa bus times

Buses run 3 times a week between Des Moines and Tampa. The service departs Des Moines at 7:50 AM in the morning, which arrives into Tampa at 08:15:00. All services require a transfer at Indianapolis Union Station and take an average of 47h 25m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 25m • 2 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 25m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USA47h 25m • 2 changes

Frequently asked questions

Want to know about travelling from Des Moines to Tampa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Tampa.ExpandLaunch map view
  • Distance: 1,523.4 mi
  • Duration: 47h 25m

What companies run services between Des Moines, IA, USA and Tampa, FL, USA?

You can take a bus from Des Moines to Tampa Bus Station via Indianapolis Union Station and Atlanta Bus Station in around 32h 20m.

Operators