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Des Plaines to Indianapolis buses

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Trip Overview

The average bus between Des Plaines and Indianapolis takes 6h 56m and the fastest bus takes 5h 47m. The bus service runs several times per day from Des Plaines to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 56m
Duration
198 mi
Distance
$48
Average price
4 times a day
Frequency

Bus (Greyhound)

best
  1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
4h 55m
$37–58

Des Plaines to Indianapolis bus times

Buses run 4 times a day between Des Plaines and Indianapolis. The earliest departure is at 5:03 AM in the morning, and the last departure from Des Plaines is at 6:31 PM which arrives into Indianapolis at 11:50 AM. All services require a transfer at Chicago OTC and take an average of 6h 56m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

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    Arrives next day

    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 33m • 3 changes

Departing Thursday, October 22, 2026

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 18m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 28m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 38m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA7h 17m • 3 changes
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Departing Friday, October 23, 2026

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA5h 47m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 18m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 28m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 38m • 3 changes
  • Show more

Departing Monday, October 26, 2026

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA5h 47m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 18m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 28m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 38m • 3 changes
  • Show more

Departing Tuesday, October 27, 2026

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA5h 47m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 18m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 28m • 3 changes

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    Pace BusChicago Transit (CTA)Chicago Transit (CTA)Flixbus USA6h 38m • 3 changes
  • Show more

Frequently asked questions

Want to know about travelling from Des Plaines to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Plaines to Indianapolis.ExpandLaunch map view
  • Distance: 197.5 mi
  • Duration: 6h 56m

What companies run services between Des Plaines, IL, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station 5 times a day. Tickets cost $30–50 and the journey takes 3h 5m.

Operators