The average bus between Des Plaines and St. Louis takes 9h 3m and the fastest bus takes 7h 45m. The bus service runs several times per day from Des Plaines to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Des Plaines and St. Louis. The earliest departure is at 7:00 AM in the morning, and the last departure from Des Plaines is at 7:30 PM which arrives into St. Louis at 6:20 AM. All services require a transfer at Illinois Terminal and take an average of 9h 3m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Plaines to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Plaines to St. Louis. However, there are services departing from O'Hare Multi-Modal Facility station and arriving at St Louis Bus Station via Illinois Terminal station. The journey, including transfers, takes approximately 9h 3m.
Des Plaines to St. Louis bus services, operated by Peoria Charter Coach Company, depart from O'Hare Multi-Modal Facility station.
Des Plaines to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
The distance between Des Plaines and St. Louis is 426.5 km. The road distance is 480 km.
You can take a bus from O'Hare Multi-Modal Facility to St Louis Bus Station via Illinois Terminal and Champaign Intermodal Trans Ctr in around 8h.
