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Detroit Airport (DTW) to Key Largo buses

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Trip Overview

The average bus between Detroit Airport (DTW) and Key Largo takes 2d 2h and the fastest bus takes 2d. The bus runs, on average, 5 times per week from Detroit Airport (DTW) to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 2h
Duration
1,497 mi
Distance
$326
Average price
5 times a week
Frequency

Detroit Airport (DTW) to Key Largo bus times

Buses run 5 times a week between Detroit Airport (DTW) and Key Largo. The earliest departure is at 5:35 AM in the morning, and the last departure from Detroit Airport (DTW) is at 11:03 PM which arrives into Key Largo at 6:25 AM. All services require a transfer at Cass & Michigan and take an average of 2d 2h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Southeast Michigan SMARTDDotGreyhound USAFlixbus USAGreyhound USA2d • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Southeast Michigan SMARTDDotGreyhound USAFlixbus USAGreyhound USA2d • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Southeast Michigan SMARTDDotGreyhound USAFlixbus USAGreyhound USA2d • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Southeast Michigan SMARTDDotGreyhound USAFlixbus USAGreyhound USA2d • 4 changes
  •  → 

    Arrives +3 days

    Southeast Michigan SMARTDDotGreyhound USAFlixbus USAGreyhound USA2d 7h • 4 changes

Frequently asked questions

Want to know about travelling from Detroit Airport (DTW) to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Detroit Airport (DTW) to Key Largo.ExpandLaunch map view
  • Distance: 1,497.1 mi
  • Duration: 2d 2h

What companies run services between Detroit Airport (DTW), USA and Key Largo, FL, USA?

You can take a bus from Metro Airport McNamara Terminal to Key Largo Bus Stop via Cass & Michigan, Rosa Parks Transit Center - Bay 10, Lafayette & Fifth, Detroit Bus Station, Atlanta Bus Station, and Miami Airport Station in around 35h 20m.

Operators