Rome2Rio

Detroit to Florence buses

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Trip Overview

The bus between Detroit and Florence takes 2d. The bus runs, on average, 5 times per week from Detroit to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
809 mi
Distance
$150
Average price
5 times a week
Frequency

Detroit to Florence bus times

Buses run 5 times a week between Detroit and Florence. The service departs Detroit at 12:35 PM in the afternoon, which arrives into Florence at 13:30:00. All services require a transfer at Columbus and take an average of 2d. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Barons BusBarons BusGreyhound USAGreyhound USA2d • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Barons BusBarons BusGreyhound USAGreyhound USA2d • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Barons BusBarons BusGreyhound USAGreyhound USA2d • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Barons BusBarons BusGreyhound USAGreyhound USA2d • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Barons BusBarons BusGreyhound USAGreyhound USA2d • 3 changes

Frequently asked questions

Want to know about travelling from Detroit to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Detroit to Florence.ExpandLaunch map view
  • Distance: 809.3 mi
  • Duration: 2d

What companies run services between Detroit, MI, USA and Florence, SC, USA?

You can take a bus from Detroit to Florence Bus Station via Columbus, Charlotte Bus Station, and Camden in around 20h 10m.

Operators