Rome2Rio

Detroit to Jeffersonville buses

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Trip Overview

The average bus between Detroit and Jeffersonville takes 25h 3m and the fastest bus takes 17h 28m. The bus runs, on average, 3 times per week from Detroit to Jeffersonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 3m
Duration
397 mi
Distance
$89
Average price
3 times a week
Frequency

Detroit to Jeffersonville bus times

Buses run 3 times a week between Detroit and Jeffersonville. The service departs Detroit at 1:50 PM in the afternoon, which arrives into Jeffersonville at 06:03:00. All services require a transfer at Indianapolis Union Station and take an average of 25h 3m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAAmtrak ThruwayTransit Authority of River City40h 13m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City17h 28m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City17h 28m • 2 changes

Frequently asked questions

Want to know about travelling from Detroit to Jeffersonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Detroit to Jeffersonville.ExpandLaunch map view
  • Distance: 396.9 mi
  • Duration: 25h 3m

What companies run services between Detroit, MI, USA and Jeffersonville, IN, USA?

You can take a bus from Detroit Bus Station to Court @ Spring via Indianapolis Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 9h 22m.

Operators