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Detroit to Louisville, KY buses

Find Transport to Louisville, KY

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Trip Overview

The average bus between Detroit and Louisville, KY takes 7h 43m and the fastest bus takes 7h 25m. The bus service runs several times per day from Detroit to Louisville, KY. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 43m
Duration
358 mi
Distance
$80
Average price
Twice daily
Frequency

Detroit to Louisville, KY bus times

Buses run twice daily between Detroit and Louisville, KY. The earliest departure is at 1:50 PM in the afternoon, and the last departure from Detroit is at 7:30 PM which arrives into Louisville, KY at 2:55 AM. All services run direct with no transfers required, and take on average 7h 43m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Saturday, November 7, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Monday, November 9, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Tuesday, November 10, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Wednesday, November 11, 2026

  •  → 

    bus bus 8h 5m • Direct
  •  → 

    Arrives next day

    bus bus 7h 25m • Direct

Departing Thursday, November 12, 2026

  •  → 

    bus bus 8h 5m • Direct

Frequently asked questions

Want to know about travelling from Detroit to Louisville, KY? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Detroit to Louisville, KY.ExpandLaunch map view
  • Distance: 357.7 mi
  • Duration: 7h 43m

What companies run services between Detroit, MI, USA and Louisville, KY, USA?

Greyhound USA operates a bus from Detroit Bus Station to Louisville Bus Station 4 times a day. Tickets cost $65–100 and the journey takes 7h 25m.

Operators