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Detroit to Mechanicsburg buses

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Trip Overview

The bus between Detroit and Mechanicsburg takes 18h 53m. The bus runs, on average, 5 times per week from Detroit to Mechanicsburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 53m
Duration
510 mi
Distance
$111
Average price
5 times a week
Frequency

Detroit to Mechanicsburg bus times

Buses run 5 times a week between Detroit and Mechanicsburg. The service departs Detroit at 11:05 AM in the morning, which arrives into Mechanicsburg at 05:58:03. All services require a transfer at Harrisburg Bus Station and take an average of 18h 53m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Greyhound USARabbit Transit18h 53m • 1 change

Departing Monday, November 9, 2026

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    Arrives next day

    Greyhound USARabbit Transit18h 53m • 1 change

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USARabbit Transit18h 53m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USARabbit Transit18h 53m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USARabbit Transit18h 53m • 1 change

Frequently asked questions

Want to know about travelling from Detroit to Mechanicsburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Detroit to Mechanicsburg.ExpandLaunch map view
  • Distance: 510.2 mi
  • Duration: 18h 53m

What companies run services between Detroit, MI, USA and Mechanicsburg, Cumberland County, PA, USA?

Greyhound USA operates a bus from Detroit Bus Station to Harrisburg Bus Station twice daily. Tickets cost $90–140 and the journey takes 13h 5m.

Operators