The average bus between Domodossola and Genoa takes 5h 59m and the fastest bus takes 5h 5m. The bus service runs several times per day from Domodossola to Genoa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Domodossola and Genoa. The earliest departure is at 6:00 AM in the morning, and the last departure from Domodossola is at 7:35 PM which arrives into Genoa at 2:40 AM. All services require a transfer at Rho Fiera Milano and take an average of 5h 59m. The schedules shown below are for the next available departures.

5h 55m • 1 change

5h 5m • 1 change
Arrives next day

7h 5m • 1 change

6h • 1 change

5h 55m • 1 change

5h 5m • 1 change
Arrives next day

7h 5m • 1 change

6h • 1 change

5h 55m • 1 change

5h 5m • 1 change
Arrives next day

7h 5m • 1 change

6h • 1 change

5h 55m • 1 change

5h 5m • 1 change
Arrives next day

7h 5m • 1 change
Want to know about travelling from Domodossola to Genoa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Domodossola to Genoa. However, there are services departing from Domodossola station and arriving at Genoa station via Rho Fiera Milano. The journey, including transfers, takes approximately 5h 59m.
Domodossola to Genoa bus services, operated by Autoservizi Comazzi srl, depart from Domodossola station.
Domodossola to Genoa bus services, operated by Autoservizi Comazzi srl, arrive at Genoa station.
The distance between Domodossola and Genoa is 197 km. The road distance is 276 km.
You can take a bus from Domodossola to Genoa via Rho Fiera Milano, Rho Fieramilano, Lampugnano, and Milano, Autostazione Lampugnano in around 4h 43m.