The average bus between Domodossola and Ispra takes 2h 10m and the fastest bus takes 1h 17m. The bus service runs several times per day from Domodossola to Ispra. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Domodossola and Ispra. The earliest departure is at 5:55 AM in the morning, and the last departure from Domodossola is at 6:55 PM which arrives into Ispra at 8:38 PM. All services require a transfer, and take on average 2h 10m. The schedules shown below are for the next available departures.

1h 34m • 1 change
5h 43m • 1 change
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1h 17m • 1 change
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1h 17m • 1 change
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1h 43m • 1 change
1h 17m • 1 change
1h 34m • 1 change
5h 43m • 1 change
1h 43m • 1 change
1h 17m • 1 change
1h 34m • 1 change
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1h 17m • 1 change
1h 34m • 1 change
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1h 43m • 1 changeWant to know about travelling from Domodossola to Ispra? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Domodossola to Ispra. However, there are services departing from Domodossola station and arriving at Ispra station via Sesto Calende station. The journey, including transfers, takes approximately 2h 10m.
Domodossola to Ispra bus services, operated by Trenord, depart from Domodossola station.
Domodossola to Ispra bus services, operated by Trenord, arrive at Ispra station.
The distance between Domodossola and Ispra is 41.5 km. The road distance is 86 km.
You can take a bus from Domodossola to Ispra via Sesto Calende in around 2h 4m.