The average bus between Domodossola and Lyon takes 9h 15m and the fastest bus takes 8h 20m. The bus service runs several times per day from Domodossola to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Domodossola and Lyon. The earliest departure is at 9:35 AM in the morning, and the last departure from Domodossola is at 7:35 PM which arrives into Lyon at 3:55 AM. All services require a transfer at Aeroporto Malpensa - Terminal 1 and take an average of 9h 15m. The schedules shown below are for the next available departures.


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9h 35m • 2 changes

9h 15m • 2 changesArrives next day


9h 55m • 2 changes

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9h 15m • 2 changesArrives next day


9h 55m • 2 changes

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9h 15m • 2 changesArrives next day


9h 55m • 2 changes

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9h 15m • 2 changesArrives next day


9h 55m • 2 changes

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9h 25m • 2 changesArrives next day


9h 55m • 2 changesWant to know about travelling from Domodossola to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Domodossola to Lyon. However, there are services departing from Domodossola station and arriving at Lyon station via Aeroporto Malpensa - Terminal 1. The journey, including transfers, takes approximately 9h 15m.
Domodossola to Lyon bus services, operated by Autoservizi Comazzi srl, depart from Domodossola - Stazione Ferroviaria station.
Domodossola to Lyon bus services, operated by Autoservizi Comazzi srl, arrive at Lyon - Gerland Bus Station.
The distance between Domodossola and Lyon is 269.6 km. The road distance is 521 km.
You can take a bus from Domodossola - Stazione Ferroviaria to Lyon - Gerland Bus Station via Aeroporto Malpensa - Terminal 1, Milan, and Turin - Vittorio Emanuele Bus Station in around 8h 44m.