The average bus between Dortmund and Neu-Isenburg takes 4h 41m and the fastest bus takes 4h 18m. The bus service runs several times per day from Dortmund to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Dortmund and Neu-Isenburg. The earliest departure is at 5:10 AM in the morning, and the last departure from Dortmund is at 7:15 PM which arrives into Neu-Isenburg at 1:33 AM. All services require a transfer at Frankfurt Airport and take an average of 4h 41m. The schedules shown below are for the next available departures.

4h 42m • 1 change

6h 57m • 1 change
Arrives next day

6h 18m • 1 change

4h 42m • 1 change

6h 57m • 1 change
Arrives next day

6h 18m • 1 change

4h 42m • 1 change

6h 57m • 1 change
Arrives next day

6h 18m • 1 change

4h 42m • 1 change

6h 57m • 1 change
Arrives next day

6h 18m • 1 change
Want to know about travelling from Dortmund to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Dortmund to Neu-Isenburg. However, there are services departing from Dortmund station and arriving at Neu-Isenburg station via Frankfurt Airport. The journey, including transfers, takes approximately 4h 41m.
Dortmund to Neu-Isenburg bus services, operated by FlixBus, depart from Dortmund central bus station.
Dortmund to Neu-Isenburg bus services, operated by FlixBus, arrive at Frankfurt Airport station.
The distance between Dortmund and Neu-Isenburg is 184.5 km. The road distance is 244 km.
FlixBus operates a bus from Dortmund central bus station to Frankfurt Airport 5 times a day. Tickets cost €19–35 and the journey takes 3h 45m.