The average bus between Downingtown and Salisbury takes 10h 43m and the fastest bus takes 7h 40m. The bus service runs several times per day from Downingtown to Salisbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Downingtown and Salisbury. The earliest departure is at 7:51 AM in the morning, and the last departure from Downingtown is at 8:51 PM which arrives into Salisbury at 2:40 PM. All services require a transfer at West Chester Transit Center and take an average of 10h 43m. The schedules shown below are for the next available departures.




7h 52m • 4 changes




7h 56m • 4 changes




8h 56m • 4 changes
Arrives next day




18h 19m • 4 changes




7h 52m • 4 changes




7h 56m • 4 changes




8h 56m • 4 changes
Arrives next day




18h 19m • 4 changes
Want to know about travelling from Downingtown to Salisbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Downingtown to Salisbury. However, there are services departing from Downingtown station and arriving at Salisbury station via Baltimore Downtown Bus Station station. The journey, including transfers, takes approximately 10h 43m.
Downingtown to Salisbury bus services, operated by SEPTA, depart from Philadelphia Bus Station.
Downingtown to Salisbury bus services, operated by SEPTA, arrive at Salisbury, MD station.
The distance between Downingtown and Salisbury is 183.2 km. The road distance is 422 km.
You can take a bus from Lancaster Av & Green St - MBNS to Salisbury, MD via West Chester Transit Center, 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, Baltimore Downtown Bus Station, and Baltimore, MD - Greyhound Bus Terminal Downtown in around 9h 20m.