The average bus between Downtown San Diego and San Ysidro takes 1h 33m and the fastest bus takes 1h 12m. The bus runs at least 2 times per hour from Downtown San Diego to San Ysidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 30 minutes between Downtown San Diego and San Ysidro. The earliest departure is at 12:34 AM at night, and the last departure from Downtown San Diego is at 11:34 PM which arrives into San Ysidro at 1:01 AM. All services require a transfer at Broadway & 8th Av and take an average of 1h 33m. The schedules shown below are for the next available departures.

1h 28m • 1 change

1h 27m • 1 change
Arrives next day

5h 57m • 1 change

1h 17m • 1 change

1h 20m • 1 change

1h 30m • 1 change

1h 26m • 1 change

4h 57m • 1 change

1h 17m • 1 change

1h 20m • 1 change

1h 30m • 1 change
Want to know about travelling from Downtown San Diego to San Ysidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Downtown San Diego to San Ysidro. However, there are services departing from Downtown San Diego station and arriving at San Ysidro station via Iris Avenue Transit Center. The journey, including transfers, takes approximately 1h 33m.
Downtown San Diego to San Ysidro bus services, operated by San Diego Metro Transit, depart from Broadway & 8th Av station.
Downtown San Diego to San Ysidro bus services, operated by San Diego Metro Transit, arrive at Iris Avenue Transit Center station.
The distance between Downtown San Diego and San Ysidro is 21.4 km. The road distance is 35 km.
San Diego Metro Transit operates a bus from Broadway & 8th Av to Iris Avenue Transit Center every 30 minutes. Tickets cost $2–5 and the journey takes 1h 2m.