The average bus between Dresden Hbf and Brno takes 4h 57m and the fastest bus takes 4h 25m. There is a bus service every few hours from Dresden Hbf to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Dresden Hbf and Brno. The earliest departure is at 1:45 AM at night, and the last departure from Dresden Hbf is at 8:50 PM which arrives into Brno at 1:55 AM. All services require a transfer, and take on average 4h 57m. The schedules shown below are for the next available departures.

5h 5m • 1 change

5h 5m • 1 change

4h 50m • 1 change

4h 50m • 1 change

4h 25m • 1 change

5h 5m • 1 change

5h 5m • 1 change

4h 50m • 1 change

4h 25m • 1 change

5h 5m • 1 change

5h 5m • 1 change

4h 50m • 1 change
Want to know about travelling from Dresden Hbf to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Dresden Hbf to Brno. However, there are services departing from Dresden Hbf station and arriving at Brno station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 4h 57m.
Dresden Hbf to Brno bus services, operated by FlixBus, depart from Dresden central station.
Dresden Hbf to Brno bus services, operated by FlixBus, arrive at Brno station.
Book your Dresden Hbf to Brno bus tickets online with FlixBus.
The distance between Dresden Hbf and Brno is 290 km. The road distance is 359 km.
You can take a bus from Dresden central station to Brno via Praha, ÚAN Florenc in around 5h.