The average bus between Duisburg and Brussels takes 5h 34m and the fastest bus takes 3h 55m. The bus service runs several times per day from Duisburg to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Duisburg and Brussels. The earliest departure is at 7:25 AM in the morning, and the last departure from Duisburg is at 11:59 PM which arrives into Brussels at 7:30 AM. All services require a transfer, and take on average 5h 34m. The schedules shown below are for the next available departures.

6h 5m • 1 change

6h 25m • 1 change

4h 35m • 1 change

5h • 1 change

3h 55m • 1 change

6h 25m • 1 change

4h 35m • 1 change

5h • 1 change

3h 55m • 1 change

6h 25m • 1 change

4h 35m • 1 change

5h • 1 change

4h 10m • 1 change

6h 25m • 1 change

4h 35m • 1 change

5h • 1 change

3h 55m • 1 change

6h 25m • 1 change

4h 35m • 1 change

5h • 1 change
Want to know about travelling from Duisburg to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Duisburg to Brussels. However, there are services departing from Duisburg station and arriving at Brussels station via Brussels-North train station station. The journey, including transfers, takes approximately 5h 34m.
Duisburg to Brussels bus services, operated by FlixBus, depart from Düsseldorf central bus station.
Duisburg to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Book your Duisburg to Brussels bus tickets online with FlixBus.
The distance between Duisburg and Brussels is 180.6 km. The road distance is 225 km.
FlixBus operates a bus from Düsseldorf central bus station to Brussels-North train station every 4 hours. Tickets cost €17–28 and the journey takes 2h 40m.