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Duke University to Charleston buses

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Trip Overview

The average bus between Duke University and Charleston takes 21h 13m and the fastest bus takes 18h 58m. There is at least one bus per day from Duke University to Charleston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 13m
Duration
356 mi
Distance
$80
Average price
Once daily
Frequency

Duke University to Charleston bus times

Buses run once daily between Duke University and Charleston. The earliest departure is at 8:40 PM in the evening, and the last departure from Duke University is at 8:41 PM which arrives into Charleston at 3:41 PM. All services require a transfer at Flowers Dr at Duke Gardens and take an average of 21h 13m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    GoDurhamFlixbus USAGreyhound USACARTACARTA19h 1m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    GoDurhamFlixbus USAGreyhound USACARTACARTA18h 58m • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    GoDurhamFlixbus USAGreyhound USACARTACARTA34h 29m • 4 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    GoDurhamFlixbus USAGreyhound USACARTACARTA19h • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    GoDurhamFlixbus USAGreyhound USACARTACARTA19h 1m • 4 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    GoDurhamFlixbus USAGreyhound USACARTACARTA19h 1m • 4 changes

Frequently asked questions

Want to know about travelling from Duke University to Charleston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Duke University to Charleston.ExpandLaunch map view
  • Distance: 356 mi
  • Duration: 21h 13m

What companies run services between Duke University, NC, USA and Charleston, SC, USA?

Greyhound USA operates a bus from Raleigh Bus Station to Charleston Bus Station twice daily. Tickets cost $55–90 and the journey takes 7h 5m.

Operators