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Duke University to Winston-Salem buses

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Trip Overview

The average bus between Duke University and Winston-Salem takes 4h 12m and the fastest bus takes 2h 23m. The bus service runs several times per day from Duke University to Winston-Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 12m
Duration
82 mi
Distance
$18
Average price
3 times a day
Frequency

Duke University to Winston-Salem bus times

Buses run 3 times a day between Duke University and Winston-Salem. The earliest departure is at 1:40 PM in the afternoon, and the last departure from Duke University is at 11:40 PM which arrives into Winston-Salem at 6:45 AM. All services require a transfer at Flowers Dr at Duke Gardens and take an average of 4h 12m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
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    GoDurhamGreyhound USA2h 24m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA7h 4m • 1 change

Departing Friday, November 13, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 24m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA7h 4m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 24m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA7h 4m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    GoDurhamGreyhound USA2h 43m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 23m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA10h 3m • 1 change

Departing Monday, November 16, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 24m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA7h 4m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 24m • 1 change
  •  → 

    Arrives next day

    GoDurhamGreyhound USA7h 4m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    GoDurhamGreyhound USA2h 44m • 1 change
  •  → 

    GoDurhamGreyhound USA2h 24m • 1 change

Frequently asked questions

Want to know about travelling from Duke University to Winston-Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Duke University to Winston-Salem.ExpandLaunch map view
  • Distance: 82.1 mi
  • Duration: 4h 12m

What companies run services between Duke University, NC, USA and Winston-Salem, NC, USA?

Greyhound USA operates a bus from Durham to Winston Salem(Trans Center) 3 times a day. Tickets cost $14–22 and the journey takes 1h 45m.

Operators