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Durham to Florence buses

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Trip Overview

The average bus between Durham and Florence takes 16h 15m and the fastest bus takes 12h 45m. There is at least one bus per day from Durham to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 15m
Duration
176 mi
Distance
$34
Average price
Once daily
Frequency

Durham to Florence bus times

Buses run once daily between Durham and Florence. The earliest departure is at 9:00 AM in the morning, and the last departure from Durham is at 9:15 PM which arrives into Florence at 10:00 AM. All services require a transfer, and take on average 16h 15m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

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    Arrives next day

    Flixbus USAGreyhound USA12h 45m • 1 change

Departing Saturday, October 17, 2026

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    Arrives next day

    Flixbus USAGreyhound USA12h 45m • 1 change

Departing Sunday, October 18, 2026

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    Arrives next day

    Flixbus USAGreyhound USA12h 45m • 1 change

Departing Monday, October 19, 2026

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    Arrives next day

    Flixbus USAGreyhound USA12h 45m • 1 change

Departing Tuesday, October 20, 2026

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    Arrives next day

    Greyhound USAGreyhound USA25h • 1 change

Departing Wednesday, October 21, 2026

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    Arrives next day

    Greyhound USAGreyhound USA25h • 1 change

Frequently asked questions

Want to know about travelling from Durham to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Florence.ExpandLaunch map view
  • Distance: 175.9 mi
  • Duration: 16h 15m

What companies run services between Durham, NC, USA and Florence, SC, USA?

Greyhound USA operates a bus from Raleigh Bus Station to Florence Bus Station twice daily. Tickets cost $24–40 and the journey takes 3h.

Operators