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Durham to Harrisburg, Pa buses

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Trip Overview

The average bus between Durham and Harrisburg, Pa takes 10h 18m and the fastest bus takes 9h 55m. The bus runs, on average, 4 times per week from Durham to Harrisburg, Pa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 18m
Duration
373 mi
Distance
$80
Average price
4 times a week
Frequency

Durham to Harrisburg, Pa bus times

Buses run 4 times a week between Durham and Harrisburg, Pa. The earliest departure is at 2:15 AM at night, and the last departure from Durham is at 3:50 AM which arrives into Harrisburg, Pa at 1:45 PM. All services require a transfer, and take on average 10h 18m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Flixbus USAGreyhound USA11h 30m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Flixbus USAGreyhound USA9h 55m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Flixbus USAGreyhound USA9h 55m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Flixbus USAGreyhound USA9h 55m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Harrisburg, Pa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 373.4 mi
  • Duration: 10h 18m

What companies run services between Durham, NC, USA and Harrisburg, Pa, PA, USA?

You can take a bus from Durham to Harrisburg Bus Station via Washington Union Station in around 8h 40m.

Operators