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Durham to North Charleston buses

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Trip Overview

The average bus between Durham and North Charleston takes 20h 20m and the fastest bus takes 16h 50m. There is at least one bus per day from Durham to North Charleston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 20m
Duration
340 mi
Distance
$75
Average price
Once daily
Frequency

Durham to North Charleston bus times

Buses run once daily between Durham and North Charleston. The earliest departure is at 9:00 AM in the morning, and the last departure from Durham is at 9:15 PM which arrives into North Charleston at 2:05 PM. All services require a transfer, and take on average 20h 20m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Flixbus USAGreyhound USA16h 50m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USA29h 5m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USA29h 5m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA16h 50m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA16h 50m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA16h 50m • 1 change

Frequently asked questions

Want to know about travelling from Durham to North Charleston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to North Charleston.ExpandLaunch map view
  • Distance: 339.9 mi
  • Duration: 20h 20m

What companies run services between Durham, NC, USA and North Charleston, SC, USA?

Greyhound USA operates a bus from Raleigh Bus Station to Charleston Bus Station once daily. Tickets cost $55–90 and the journey takes 7h 5m.

Operators