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Durham to Salisbury buses

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Trip Overview

The average bus between Durham and Salisbury takes 12h 2m and the fastest bus takes 11h 40m. The bus service runs several times per day from Durham to Salisbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

12h 2m
Duration
412 mi
Distance
$179
Average price
Twice daily
Frequency

Durham to Salisbury bus times

Buses run twice daily between Durham and Salisbury. The earliest departure is at 2:15 AM at night, and the last departure from Durham is at 9:00 AM which arrives into Salisbury at 8:40 PM. All services require a transfer, and take on average 12h 2m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Flixbus USABayRunner Shuttle12h 25m • 1 change
  •  → 

    Greyhound USABayRunner Shuttle11h 40m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Salisbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Salisbury.ExpandLaunch map view
  • Distance: 412.5 mi
  • Duration: 12h 2m

What companies run services between Durham, NC, USA and Salisbury, MD, USA?

You can take a bus from Durham to Salisbury via Baltimore in around 9h 55m.

Operators