The average bus between East Boston and Hyannis takes 2h 4m and the fastest bus takes 1h 52m. The bus service runs several times per day from East Boston to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between East Boston and Hyannis. The earliest departure is at 7:26 AM in the morning, and the last departure from East Boston is at 7:37 PM which arrives into Hyannis at 9:35 PM. All services require a transfer at South Station and take an average of 2h 4m. The schedules shown below are for the next available departures.

2h 5m • 1 change
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1h 59m • 1 change
1h 52m • 1 change
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1h 59m • 1 change
1h 52m • 1 change
2h 9m • 1 change
2h 12m • 1 change
1h 59m • 1 change
1h 52m • 1 change
2h 9m • 1 change
2h 12m • 1 change
1h 59m • 1 change
1h 52m • 1 change
2h 9m • 1 change
2h 12m • 1 change
1h 59m • 1 change
1h 52m • 1 changeWant to know about travelling from East Boston to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from East Boston to Hyannis. However, there are services departing from East Boston station and arriving at Hyannis station via Hyannis. The journey, including transfers, takes approximately 2h 4m.
East Boston to Hyannis bus services, operated by MBTA, depart from Boston station.
East Boston to Hyannis bus services, operated by MBTA, arrive at Hyannis station.
The distance between East Boston and Hyannis is 101.7 km. The road distance is 123 km.
Peter Pan Bus Lines operates a bus from Boston to Hyannis every 3 hours. Tickets cost $16–35 and the journey takes 1h 40m.