The average bus between East Kilbride and Manchester takes 5h 37m and the fastest bus takes 4h 43m. The bus service runs several times per day from East Kilbride to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between East Kilbride and Manchester. The earliest departure is at 7:49 AM in the morning, and the last departure from East Kilbride is at 9:57 PM which arrives into Manchester at 2:40 AM. All services require a transfer at Buchanan Street and take an average of 5h 37m. The schedules shown below are for the next available departures.

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5h 53m • 1 change
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5h 4m • 1 change
Want to know about travelling from East Kilbride to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from East Kilbride to Manchester. However, there are services departing from East Kilbride station and arriving at Manchester station via Shudehill Interchange. The journey, including transfers, takes approximately 5h 37m.
East Kilbride to Manchester bus services, operated by First Greater Glasgow, depart from Buchanan Bus Station.
East Kilbride to Manchester bus services, operated by First Greater Glasgow, arrive at Shudehill Interchange station.
Book your East Kilbride to Manchester bus tickets online with First Greater Glasgow and FlixBus.
The distance between East Kilbride and Manchester is 282.9 km. The road distance is 357 km.
FlixBus operates a bus from Buchanan Bus Station to Shudehill Interchange hourly. Tickets cost £24–45 and the journey takes 4h.