The average bus between East Setauket and Central Islip takes 1h 33m and the fastest bus takes 1h 7m. There is an hourly bus service from East Setauket to Central Islip. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between East Setauket and Central Islip. The earliest departure is at 5:10 AM in the morning, and the last departure from East Setauket is at 10:07 PM which arrives into Central Islip at 6:47 AM. All services require a transfer, and take on average 1h 33m. The schedules shown below are for the next available departures.

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1h 11m • 1 changeWant to know about travelling from East Setauket to Central Islip? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from East Setauket to Central Islip. However, there are services departing from East Setauket station and arriving at Central Islip station via Smith Haven Mall. The journey, including transfers, takes approximately 1h 33m.
East Setauket to Central Islip bus services, operated by Suffolk County Transit, depart from NYS 25A/Main St station.
East Setauket to Central Islip bus services, operated by Suffolk County Transit, arrive at W Suffolk Ave/Wheeler Rd station.
The distance between East Setauket and Central Islip is 18.6 km. The road distance is 26 km.
You can take a bus from NYS 25A/Main St to W Suffolk Ave/Wheeler Rd via Smith Haven Mall in around 1h 25m.