The average bus between East Setauket and West Islip takes 2h 35m and the fastest bus takes 2h 16m. There is an hourly bus service from East Setauket to West Islip. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between East Setauket and West Islip. The earliest departure is at 5:10 AM in the morning, and the last departure from East Setauket is at 10:09 PM which arrives into West Islip at 6:31 AM. All services require a transfer, and take on average 2h 35m. The schedules shown below are for the next available departures.

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2h 24m • 1 change

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2h 17m • 1 change

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Want to know about travelling from East Setauket to West Islip? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from East Setauket to West Islip. However, there are services departing from East Setauket station and arriving at West Islip station via Patchogue LIRR. The journey, including transfers, takes approximately 2h 35m.
East Setauket to West Islip bus services, operated by Suffolk County Transit, depart from NYS 25A/Main St station.
East Setauket to West Islip bus services, operated by Suffolk County Transit, arrive at Montauk Hwy/Eaton Ln station.
The distance between East Setauket and West Islip is 31.1 km. The road distance is 68 km.
You can take a bus from NYS 25A/Main St to Montauk Hwy/Eaton Ln via Patchogue LIRR in around 2h 37m.