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Effingham to Buffalo buses

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Trip Overview

The average bus between Effingham and Buffalo takes 29h 45m and the fastest bus takes 29h 35m. The bus runs, on average, 6 times per week from Effingham to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 45m
Duration
665 mi
Distance
$126
Average price
6 times a week
Frequency

Effingham to Buffalo bus times

Buses run 6 times a week between Effingham and Buffalo. The service departs Effingham at 4:05 PM in the afternoon, which arrives into Buffalo at 22:40:00. All services require a transfer at Indianapolis and take an average of 29h 45m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

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    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus30h 35m • 3 changes

Departing Sunday, November 1, 2026

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    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus29h 35m • 3 changes

Departing Monday, November 2, 2026

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    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus29h 35m • 3 changes

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus29h 35m • 3 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus29h 35m • 3 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Greyhound USABarons BusBarons BusBarons Bus29h 35m • 3 changes

Frequently asked questions

Want to know about travelling from Effingham to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Effingham to Buffalo.ExpandLaunch map view
  • Distance: 664.6 mi
  • Duration: 29h 45m

What companies run services between Effingham, IL, USA and Buffalo, NY, USA?

You can take a bus from Effingham to Buffalo via Indianapolis, Toledo, and Cleveland in around 14h 30m.

Operators