Rome2Rio

Effingham to Port Saint Lucie buses

Find Transport to Port Saint Lucie

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Effingham and Port Saint Lucie takes 31h 27m and the fastest bus takes 27h 55m. The bus runs, on average, 6 times per week from Effingham to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

31h 27m
Duration
1,238 mi
Distance
$252
Average price
6 times a week
Frequency

Effingham to Port Saint Lucie bus times

Buses run 6 times a week between Effingham and Port Saint Lucie. The service departs Effingham at 6:30 AM in the morning, which arrives into Port Saint Lucie at 11:52:00. All services require a transfer at St Louis Bus Station and take an average of 31h 27m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie28h 22m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie28h 22m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie28h 22m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie27h 55m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie47h 22m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USAArea Regional Transit St Lucie28h 22m • 3 changes

Frequently asked questions

Want to know about travelling from Effingham to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Effingham to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,237.8 mi
  • Duration: 31h 27m

What companies run services between Effingham, IL, USA and Port Saint Lucie, FL, USA?

You can take a bus from Effingham to SW PSL Blvd & SE Bayshore Blvd via St Louis Bus Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 27h 44m.

Operators