Rome2Rio

Empoli to Sicily buses

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Trip Overview

The average bus between Empoli and Sicily takes 24h 44m and the fastest bus takes 24h 43m. The bus runs, on average, 4 times per week from Empoli to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 44m
Duration
1,306 km
Distance
€145
Average price
4 times a week
Frequency

Empoli to Sicily bus times

Buses run 4 times a week between Empoli and Sicily. The service departs Empoli at 9:40 AM in the morning, which arrives into Sicily at 11:23:00. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 24h 44m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 47m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Frequently asked questions

Want to know about travelling from Empoli to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Empoli to Sicily.ExpandLaunch map view
  • Distance: 1,306.1 km
  • Duration: 24h 44m

What companies run services between Empoli, Tuscany, Italy and Sicily, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Palermo twice daily. Tickets cost €110–170 and the journey takes 17h.

Operators