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Empoli to Sicily buses

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Trip Overview

The average bus between Empoli and Sicily takes 24h 45m and the fastest bus takes 24h 43m. The bus runs, on average, 5 times per week from Empoli to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 45m
Duration
1,306 km
Distance
€135
Average price
5 times a week
Frequency

Empoli to Sicily bus times

Buses run 5 times a week between Empoli and Sicily. The earliest departure is at 8:40 AM in the morning, and the last departure from Empoli is at 9:40 AM which arrives into Sicily at 11:23 AM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 24h 45m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 56m • 2 changes

Departing Sunday, October 25, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Departing Monday, October 26, 2026

  •  → 

    Arrives next day

    FlixBusFlixBusAMAT Palermo S.p.A.24h 43m • 2 changes

Frequently asked questions

Want to know about travelling from Empoli to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Empoli to Sicily.ExpandLaunch map view
  • Distance: 1,306.1 km
  • Duration: 24h 45m

What companies run services between Empoli, Tuscany, Italy and Sicily, Italy?

FlixBus operates a bus from Florence Villa Constanza Bus Station to Palermo twice daily. Tickets cost €110–170 and the journey takes 17h.

Operators