The average bus between Epen and Frankfurt am Main takes 5h 48m and the fastest bus takes 5h 8m. The bus service runs several times per day from Epen to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Epen and Frankfurt am Main. The earliest departure is at 7:27 AM in the morning, and the last departure from Epen is at 11:31 PM which arrives into Frankfurt am Main at 5:50 AM. All services require a transfer at Maastricht, Station Maastricht and take an average of 5h 48m. The schedules shown below are for the next available departures.

5h 28m • 1 change

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Arrives next day

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Want to know about travelling from Epen to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Epen to Frankfurt am Main. However, there are services departing from Epen station and arriving at Frankfurt am Main station via Frankfurt central train station station. The journey, including transfers, takes approximately 5h 48m.
Epen to Frankfurt am Main bus services, operated by Arriva NL, depart from Maastricht station.
Epen to Frankfurt am Main bus services, operated by Arriva NL, arrive at Frankfurt central train station.
The distance between Epen and Frankfurt am Main is 209.6 km. The road distance is 307 km.
FlixBus operates a bus from Maastricht to Frankfurt central train station every 4 hours. Tickets cost €24–45 and the journey takes 3h 55m. BlaBlaCar Bus also services this route once daily.