The average bus between Erfurt and Karlsruhe takes 6h 27m and the fastest bus takes 5h 45m. The bus service runs several times per day from Erfurt to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Erfurt and Karlsruhe. The earliest departure is at 2:10 AM at night, and the last departure from Erfurt is at 9:15 PM which arrives into Karlsruhe at 3:00 AM. All services require a transfer, and take on average 6h 27m. The schedules shown below are for the next available departures.

3h 55m • 1 change

7h 15m • 1 change

4h 35m • 1 change
Arrives next day

5h 45m • 1 change

3h 55m • 1 change

7h 15m • 1 change

4h 35m • 1 change
Arrives next day

5h 45m • 1 change

3h 55m • 1 change

7h 15m • 1 change

4h 35m • 1 change
Arrives next day

5h 45m • 1 change

3h 55m • 1 change

7h 15m • 1 change
Arrives next day

5h 45m • 1 change
Want to know about travelling from Erfurt to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Erfurt to Karlsruhe. However, there are services departing from Erfurt station and arriving at Karlsruhe station via Frankfurt central train station station. The journey, including transfers, takes approximately 6h 27m.
Erfurt to Karlsruhe bus services, operated by FlixBus, depart from Erfurt central train station.
Erfurt to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Book your Erfurt to Karlsruhe bus tickets online with FlixBus.
The distance between Erfurt and Karlsruhe is 288.5 km. The road distance is 407 km.
You can take a bus from Erfurt central train station to Karlsruhe central train station via Frankfurt central train station in around 5h 52m.