The average bus between Eskişehir (State) and Istanbul takes 5h 31m and the fastest bus takes 5h 15m. The bus service runs several times per day from Eskişehir (State) to Istanbul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Eskişehir (State) and Istanbul. The earliest departure is at 9:01 AM in the morning, and the last departure from Eskişehir (State) is at 7:25 PM which arrives into Istanbul at 1:00 AM. All services require a transfer at Bursa bus station and take an average of 5h 31m. The schedules shown below are for the next available departures.

5h 59m • 1 change

5h 15m • 1 change

5h 15m • 1 change
Arrives next day

5h 35m • 1 change

5h 59m • 1 change

5h 15m • 1 change

5h 15m • 1 change
Arrives next day

5h 35m • 1 change

5h 59m • 1 change

5h 15m • 1 change

5h 15m • 1 change
Arrives next day

5h 35m • 1 change

5h 59m • 1 change

5h 15m • 1 change

5h 15m • 1 change
Arrives next day

5h 35m • 1 change
Want to know about travelling from Eskişehir (State) to Istanbul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Eskişehir (State) to Istanbul. However, there are services departing from Eskişehir (State) station and arriving at Istanbul station via Bursa bus station station. The journey, including transfers, takes approximately 5h 31m.
Eskişehir (State) to Istanbul bus services, operated by Kamil Koç, depart from Eskişehir TCDD train station.
Eskişehir (State) to Istanbul bus services, operated by Kamil Koç, arrive at Esenler Otogar station.
Book your Eskişehir (State) to Istanbul bus tickets online with Kamil Koç, Pamukkale Turizm and Balikesir Uludağ.
The distance between Eskişehir (State) and Istanbul is 240.3 km. The road distance is 314 km.
You can take a bus from Eskişehir TCDD train station to Esenler Otogar via Bursa bus station and Bursa in around 4h 19m.