The average bus between Esslingen and Karlsruhe takes 1h 52m and the fastest bus takes 1h 31m. There is a bus service every few hours from Esslingen to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Esslingen and Karlsruhe. The earliest departure is at 4:59 AM at night, and the last departure from Esslingen is at 11:59 PM which arrives into Karlsruhe at 1:35 AM. All services require a transfer, and take on average 1h 52m. The schedules shown below are for the next available departures.

-19 min • 1 change

1h 36m • 1 change

1h 46m • 1 change

-4 min • 1 change

1h 31m • 1 change

1h 36m • 1 change

1h 51m • 1 change

-9 min • 1 change

1h 31m • 1 change

1h 36m • 1 change

1h 51m • 1 change

-9 min • 1 change
Want to know about travelling from Esslingen to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Esslingen to Karlsruhe. However, there are services departing from Esslingen station and arriving at Karlsruhe station via Flughafen/Messe. The journey, including transfers, takes approximately 1h 52m.
Esslingen to Karlsruhe bus services, operated by Verkehrs- und Tarifverbund Stuttgart (VVS), depart from Pliensauv. Weilstraße station.
Esslingen to Karlsruhe bus services, operated by Verkehrs- und Tarifverbund Stuttgart (VVS), arrive at Karlsruhe central train station.
The distance between Esslingen and Karlsruhe is 72.4 km. The road distance is 107 km.
You can take a bus from Pliensauv. Weilstraße to Karlsruhe central train station via Stuttgart Airport Busterminal in around 2h 36m.